Figure 1

From: Laboratory diagnosis of creatine deficiency syndromes: a technical standard and guideline of the American College of Medical Genetics and Genomics

Figure 1

Creatine metabolic pathway, including biosynthesis, uptake by cells, phosphotransfer, and conversion to creatinine. AGAT: arginine:glycine amidinotransferase; GAMT: guanidinoacetate methyltransferase; CK: creatine kinase.