Figure 4

From: Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study

Figure 4

A next-generation interpretive framework model. This model includes multiple types of -omic data and novel computational tools for pathway analysis and functional investigation of variants of unknown significance alterations. Such a model could enable the development of more refined levels of therapeutic evidence that can in turn aid in the decision-making process.