Fig 4 | Genetics in Medicine

Fig 4

From: Bacterial artificial chromosome-emulation oligonucleotide arrays for targeted clinical array-comparative genomic hybridization analyses

Fig 4

Expanded comparisons of X chromosome changes between BAC and oligo arrays. Partial plots from chromosome 21 to Y are shown for each case. A, Normal male hybridized against normal female showing a loss of all clones detecting the X chromosome and a gain of all clones detecting the Y chromosome. B, Case B6-1 shows a mosaic loss detected by clones on the X chromosome (i.e., 45,X/46,XX). C, Case C40 shows a gain detected with all the clones on the X chromosome (i.e., 47,XXX). D, Case C28 shows a gain in the steroid sulfatase (STS) region on chromosome Xp22.31 detected with three clones. E, Case C21 shows a loss in the Pelizaeus-Merzbacher disease (PMD) region on chromosome Xq22.2 detected with three clones.

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