Figure 1 | Genes & Immunity

Figure 1

From: Alternative splicing directs two IL-20R2 isoforms and is responsible for the incomplete gene knockout via the exon I ablation

Figure 1

IL-20R2 Knockout mice exhibit little inhibitory effect in IMQ-induced psoriatic phenotype. (a) Genotype confirmation of the WT and IL-20R2−/− mice. PCR primer pairs UW27/28 and UW69/hl51 were specific to WT (top) and IL-20R2−/− (bottom) mice, respectively.21 (b) The WT and IL-20R2−/− mice (both BALB/c and C57BL/6) showed little difference in IMQ-induced psoriatic phenotype. Representative photographs were shown for the WT and IL-20R2−/− mice at day 7 following the treatment with either IMQ or Vaseline as a negative control.

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