Conjunctival myxoma, Zollinger-Ellison syndrome and abnormal thickening of the inter-atrial septum: A case report and review of the literature

Abstract

Purpose To report a 36-year-old man with a slowly growing painless bulbar conjunctival mass.

Results Following excision of the lesion, histological examination was performed and a diagnosis of myxoma was made. A cardiac echogram showed thickening of the inter-atrial septum. Seventeen years previously he had had Zollinger-Ellison syndrome due to gastrinoma of the pancreas which was treated by surgical removal. A review of the literature shows ocular myxomas may be associated with endocrine abnormalities such as Cushing's syndrome, acromegaly, sexual precocity and cardiac myxoma.

Conclusion In this case we report a novel association of conjunctival myxoma with Zollinger-Ellison syndrome and inter-atrial septal thickening.

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Correspondence to K Ramaesh.

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Ramaesh, K., Wharton, S. & Dhillon, B. Conjunctival myxoma, Zollinger-Ellison syndrome and abnormal thickening of the inter-atrial septum: A case report and review of the literature. Eye 15, 309–312 (2001). https://doi.org/10.1038/eye.2001.101

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Keywords

  • Cardiac
  • Conjunctival myxoma
  • Endocrine
  • Zollinger-Ellison syndrome

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