Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

How should active toxoplasmic retinochoroiditis be treated?

Eye volume 11, pages 767–770 (1997)Cite this article

Download PDF

References

  1. Remington JS, McLeod R, Desmonts G . Toxoplasmosis. In: Remington JS, Klein JO, editors. Infectious diseases of the fetus and newborn infant. 4th ed. Philadelphia: WB Saunders, 1996:140–267.

  2. Stanford M . Acute symptomatic Toxoplasma retino-choroiditis. Eye 1996;10:3–4.

    Article  Google Scholar 

  3. McMenamin PG, Dutton GN, Hay J, Cameron S . The ultrastructural pathology of congenital murine toxo-plasmic retinochoroiditis. I. The localization and morphology of Toxoplasma cysts in the retina. Exp Eye Res 1986;43:529–43.

    CAS  Article  Google Scholar 

  4. Beaman MH, Wong S-Y, Remington JS . Cytokines, Toxoplasma and intracellular parasitism. Immunol Rev 1992;127:97–117.

    CAS  Article  Google Scholar 

  5. Holland GN, O'Connor GR, Belford R Jr, Remington JS . Toxoplasmosis. In: Pepose JS, Holland GW, Wilhelmus KR, editors. Ocular infection and immunity. St Louis: Mosby, 1996:1183–223.

  6. Rothova A . Ocular involvement in toxoplasmosis. Br J Ophthalmol 1993;77:371–7.

    CAS  Article  Google Scholar 

  7. Engstrom RE, Holland GN, Nussenblatt RB, Jabs DA . Current practices in the management of ocular toxoplasmosis. Am J Ophthalmol 1991;115:601–10.

    Article  Google Scholar 

  8. McCabe RE, Oster S . Current recommendations and future prospects in the treatment of toxoplasmosis. Drugs 1989;38:973–87.

    CAS  Article  Google Scholar 

  9. Rothova A, Meenken C, Buitenhuis HJ, Brinkman CJ, Baarsma GS, Boen-Tan TN, de Jong PTVM, Khaas-sen-Brockema N, Schweitzer CMC, Timmerman Z, de Vries J, Zaal MJW, Kiljstra A . Therapy for ocular toxoplasmosis. Am J Ophthalmol 1993;115:517–23.

    CAS  Article  Google Scholar 

  10. Mets MB, Holfels E, Boyer KM, Swisher CN, Roizen N, Stein L, Hopkins J, Withers S, Mack D, Luciano R, Patel D, Remington JS, Meier P, McLeod R . Eye manifestations of congenital toxoplasmosis. Am J Ophthalmol 1996;122:309–24.

    CAS  Article  Google Scholar 

  11. Cochereau-Massin I, Le Hoang P, Lautier-Frau M, Zerdoun E, Zazoun L, Robinet M, Marcel P, Girard B, Katlama C, Leport C, Rozenbaum W, Coulaud JP, Gentilini M . Ocular toxoplasmosis in human immunodeficiency virus-infected patients. Am J Ophthalmol 1992;114:130–5.

    CAS  Article  Google Scholar 

  12. Holland GN, Engstrom RE Jr, Glasgow BJ, Beuger BB, Daniels SA, Sidikaro Y, Harmon JA, Fischer DH, Boyer DS, Rao NA, Eagle RC Jr, Kreiger AE, Foos RY . Ocular toxoplasmosis in patients with the acquired immunodeficiency syndrome. Am J Ophthalmol 1988;106:653–67.

    CAS  Article  Google Scholar 

  13. Sande MA, Whitley RJ, McCracken GH, Lentnek A, Scheld WM . Evaluation of new anti-infective drugs for the treatment of Toxoplasma encephalitis. Clin Infect Dis 1992;15(Suppl 1);S200–5.

    Article  Google Scholar 

  14. Suzuki Y, Yang Q, Conley FK, Abrams JS, Remington JS . Antibody against interleukin-6 reduces inflammation and numbers of cysts in brains of mice with toxoplasmic encephalitis. Infect Immunol 1994;62:2773–8.

    CAS  Google Scholar 

  15. Hunter CA, Subauste CS, Remington JS . The role of cytokines in toxoplasmosis. Biotherapy 1994;7:237–47.

    CAS  Article  Google Scholar 

  16. Gazzinelli RT, Brezin A, Li Q, Nussenblatt RB, Chan C-C . Toxoplasma gondii: acquired ocular toxoplasmosis in the murine model, protective role of TNF-α and IFN-γ. Exp Parasitol 1994;78:217–29.

    CAS  Article  Google Scholar 

  17. Cesario TC, Slater LM, Kaplan HS . Effect of anti-neoplastic agents on gamma-interferon production in human peripheral blood mononuclear cells. Cancer Res 1984;44:4962–6.

    CAS  PubMed  Google Scholar 

  18. Leake J . Thousands fight for steroid justice. The Sunday Times, 27 August 1995.

  19. Acers TE . Toxoplasmic retinochoroiditis: a double blind therapeutic study. Arch Ophthalmol 1964;71:58–62.

    CAS  Article  Google Scholar 

  20. O'Connor GR, Frenkel JK . Dangers of steroid therapy in toxoplasmosis. Arch Ophthalmol 1976;94:213–6.

    CAS  Article  Google Scholar 

  21. Dubremetz JF . Toxoplasma gondii: cell biology update. In: Boothroyd JC, Komuniecki R, editors. Molecular approaches to parasitology. New York: Wiley, 1995:345–58.

  22. Tomavo S, Boothroyd JC . Interconnection between organellar functions, development and drug resistance in the protozoan parasite, Toxoplasma gondii. Int J Parasitol 1995;25:1293–9.

    CAS  Article  Google Scholar 

  23. James SL . Role of nitric oxide in parasitic infections. Microbiol Rev 1995;59:533–47.

    CAS  PubMed  PubMed Central  Google Scholar 

  24. Sibley LD, Howe DK . Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. J Infect Dis 1995;172:1561–6.

    Article  Google Scholar 

Download references

Author information

Affiliations

  1. Tennent Institute of Ophthalmology Western Infirmary, Glasgow, UK

    John Hay & Gordon N Dutton

Authors
  1. John Hay
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gordon N Dutton
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Hay, J., Dutton, G. How should active toxoplasmic retinochoroiditis be treated?. Eye 11, 767–770 (1997). https://doi.org/10.1038/eye.1997.202

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/eye.1997.202

Search

Advanced search

Quick links