Abstract
Changes in corneal thickness have been correlated with severity of diabetic retinopathy. Measuring light scatter at the central cornea may reflect the changes in corneal thickness and hence the retinopathy. This study compared the peak central corneal light scatter between 22 insulin-dependent diabetic patients with disease of at least 10 years' duration and 29 controls. No significant difference was found in the light-scattering properties of the central cornea between the two groups. This technique does not offer an alternative method of screening for diabetic retinopathy.
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Herse PR . A review of the manifestations of diabetes mellitus in the anterior eye and cornea. Am J Optom Physiol Opt 1988;65:224–30.
Marano CW, Matschinskey FM . Biochemical manifestations of diabetes mellitus in microscopic layers of the cornea and retina. Diabetes Metab Rev 1989;51:1–15.
Gobbels M, Spitznas M, Oldendoerp J . Impairment of corneal epithelial barrier function in diabetes. Graefes Arch Clin Exp Ophthalmol 1989;227:142–4.
Busted N, Olsen T, Schmitz O . Clinical observations on the corneal thickness and corneal endothelium in diabetes mellitus. Br J Ophthalmol 1981;65:687–90.
The Diabetic Retinopathy Study Research Group. Report 7: A modification of the Airlie House classification of diabetic retinopathy. Invest Ophthalmol Vis Sci 1981;21:210.
Smith GTH, Brown NAP, Shun-Shin GA . Light scatter from the human central cornea. Eye 1990;4:584–8.
Pierro L, Brancato R, Zaganelli E . Correlation of corneal thickness with blood glucose control in diabetes mellitus. Br J Ophthalmol 1981;65:687–90.
Sparrow JM, Brown NAP, Shun-Shin GA, Bron AJ . The Oxford Modular Cataract Image Analysis System. Eye 1990;4:638–48.
Harris ML, Smith GTH, Brown NAP . Inter- and intra-observer reproducibility of the new Oxford CCD Scheimpflug camera. Eye 1991;5:487–90.
Stolwijk TR, van Best JA, Oosterhuis JA, Swart W . Corneal autofluorescence: an indicator of diabetic retinopathy. Invest Ophthalmol Vis Sci 1992;33:92–7.
Herse PR . Corneal hydration control in normal and alloxan-induced diabetic rabbits. Invest Ophthalmol Vis Sci 1990;31:2205–13.
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Holden, R., Shun-Shin, G. & Brown, N. Central corneal light scatter in long-term diabetics. Eye 8, 44–45 (1994). https://doi.org/10.1038/eye.1994.8
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DOI: https://doi.org/10.1038/eye.1994.8