Orbital disease in herpes zoster ophthalmicus


Three cases of orbital inflammatory disease caused by herpes zoster are described. This extremely rare complication occurred between 5 days and 14 days following the skin eruption and slowly resolved with or without treatment. Biopsy of a chronic inflammatory lesion on the cheek of one patient demonstrated a sterile vasculitis and granulomatous Iiponecrosis, a process which may underlie the orbital disease in these patients.


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Correspondence to Geoffrey E Rose.

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Vardy, S., Rose, G. Orbital disease in herpes zoster ophthalmicus. Eye 8, 577–579 (1994). https://doi.org/10.1038/eye.1994.140

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  • Herpes zoster ophthalmicus
  • Lipogranuloma
  • Orbital inflammation

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