Abstract
The pupil cycle time (PCT) was measured in 22 HIV-positive patients and 22 age/sex-matched controls. Of the HIV-positive group, 13 (59%) met the Centre for Disease Control classification of acquired immunodeficiency syndrome (AIDS) defining illness. There was a highly statistically significant difference in the PCT between the HIV-infected group and the control group (p<0.0001, Student's t-test). Within the HIV-infected group there was no statistically significant difference in the PCT between those patients with full-blown AIDS and the others. This study suggests that HIV infection may be associated with subclinical ocular autonomic dysfunction even in the earlier stages of HIV infection.
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MacLean, H., Dhillon, B. Pupil cycle time and human immunodeficiency virus (HIV) infection. Eye 7, 785–786 (1993). https://doi.org/10.1038/eye.1993.184
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DOI: https://doi.org/10.1038/eye.1993.184
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