Abstract
Corneal transplantation, which began in Dublin early in the nineteenth century, is now widely practised. Most grafts are done for visual reasons, some to manage corneal destructive disease. The factors associated with allograft rejection are well known, but a clear graft does not mean that the transplantation procedure has been successful. Successful corneal grafts enable patients to improve their life-style. To achieve this, the graft must be transparent and free of optical aberrations, the eye must be capable of achieving good vision, and the patient must have a life-style which would benefit from a successful functioning graft. A study of patients who have had corneal grafts identified the presence of a functioning graft, the lack of need for a contact lens, and the achievement of visual acuity in the operated eye which exceeds that of the contralateral eye, as requirements for patient satisfaction.
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References
Bainey G : A game of our own—the origins of Australian Football. Melbourne. Information Australia, 1990.
Darwin E : Zoonomia or the laws of organic life. Vol II. London. J. Johnson, 1796.
Bigger SL : An inquiry into the possibility of transplanting the cornea, with the view of relieving blindness caused by several diseases of that structure. Dublin J Med Sci II: 408–17.
Zimmerman TJ : Outcomology. Editorial. Arch Ophthalmol 1990, 108: 342–3.
Williams KA, Sawyer MA, White MA, Muehlberg SM, Mahmood M, Coster DJ (on behalf of all contributors): The Australian Corneal Graft Registry, 1989 report. Adelaide. Flinders Press, 1990.
Williams KA, Ash JK, Pararajasegaram P, Mills R, Harris S, Coster DJ : Long-term outcome after corneal transplantation: visual result and patient perception of success. Ophthalmology (In Press).
Volker-Dieben HJ, D'Amaro J, Kok-van Alphen CC : Hierarchy of prognostic factors for corneal allograft survival. Aust NZ J Ophthalmol 1987, 15: 11–18.
Williams KA, White MA, Ash JK, Coster DJ : Leukocytes in the graft bed associated with corneal graft failure. Ophthalmology 1989, 96: 38–44.
Sanfilippo F, MacQueen JM, Vaughn WK, Foulks GN : Reduced graft rejection with good HLA-A and B matching in high-risk corneal transplantation. New Engl J Med 1986, 315: 29–35.
Williams KA, and Coster DJ : The role of the limbus in corneal allograft rejection. Eye 1989, 3: 158–66.
Hill JC : The use of cyclosporine in high-risk keratoplasty. Am J Ophthalmol 1989, 107: 506–10.
Borel JF : The cyclosporins. Transplant Proc 1989, 21: 810–15.
Binder PS : Selective suture removal can reduce postkeratoplasty astigmatism. Ophthalmology 1985, 92: 1412–16.
Lavery GW, Lindstrom RL, Hofer LA, Doughman DJ : The surgical management of astigmatism after penetrating keratoplasty. Ophthalmic Surgery 1985, 16: 165–9.
Meyer RF, and Musch DC : Assessment of success and complications of triple procedure surgery. Am J Ophthalmol 1987, 104: 233–40.
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Coster, D. Some factors which affect the visual outcome of corneal transplantation. Eye 5, 265–278 (1991). https://doi.org/10.1038/eye.1991.43
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DOI: https://doi.org/10.1038/eye.1991.43
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