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Monitoring ocular disease by impression cytology

Eye volume 2, pages 506–516 (1988)Cite this article

Abstract

The technique for obtaining and processing conjunctival impression cytology is described. The method of grading the stained samples is outlined. Our findings in various ocular conditions with particular emphasis on; alkali burns, uveitis, hypopyon ulcer and Botulinum toxin protective ptosis are shown. Cytology from severely damaged eyes is highly abnormal, improving as the ocular disease settles. In alkali burns a return to normal cytology does not correlate with return of corneal clarity. Loss of goblet cells is a common finding in the ocular diseases demonstrated, and appears to be a non-specific indicator of ocular problems.

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Author information

Affiliations

  1. Department of ophthalmology, St. George's Hospital Medical School, London, SW17 ORE

    G G W Adams

  2. Department of Anatomy, St. George's Hospital Medical School, London, SW17 ORE

    P N Dilly

  3. Cornea Clinic, Moorfields Eye Hospital, City Road, London, EC1V 2PD.

    G G W Adams & C M Kirkness

Authors
  1. G G W Adams
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  2. P N Dilly
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  3. C M Kirkness
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Additional information

Presented at the Annual Congress of the Ophthalmological Studies of the United Kingdom, April 1988.

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Adams, G., Dilly, P. & Kirkness, C. Monitoring ocular disease by impression cytology. Eye 2, 506–516 (1988). https://doi.org/10.1038/eye.1988.100

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  • DOI: https://doi.org/10.1038/eye.1988.100

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