Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Medical treatment of cataract

Eye volume 1, pages 542–550 (1987)Cite this article

Download PDF

References

  1. Bron AJ and Brown NAP : The pathology of cataract. In preparation.

  2. Pongor S, Ulrick PC, Bensath FA, Cerami A . Proc Natl Acad Sci 1984, 81: 2684–7.

  3. Giblin FJ, Schrimscher, Reddam JR, Dziedzic D, Reddy VN : The relative roles of catalase and the glutathione redox cycle in detoxification of H2O2 by the lens. Invest Ophthalmol Vis Sci 1987, 23: 190 (Abstr 4).

    Google Scholar 

  4. Garadi R, Lou M, Whitney A : Ascorbic acid protection against oxidative damage to lens Na+ K+ ATPase and transport systems. Invest Ophthalmol Vis sci (Suppl) 1986, 27: 277 (Abstr 59).

    Google Scholar 

  5. Fukushi S and Susuki T : Double blind test of Phacolysin effect on senile cataract. Ganka Rinsho Iho 1977, 71: 303–6.

    Google Scholar 

  6. Hightower K : Membrane-SH groups and permeability. Invest Ophthalmol Vis Sci (Suppl) 1986, 27, 8 (Abstr 9).

    Google Scholar 

  7. Datiles M, Fukui H, Kinoshita JH : Galactose cataract prevention with Sorbinil, an aldose reductase inhibitor: a light microscope study. Invest Ophthalmol Vis Sci 1982, 22: 174–9.

    CAS  PubMed  Google Scholar 

  8. Fukushi S, Merola LO, Kinoshita JH : Altering the course of cataracts in diabetic rats. Invest Ophthalmol Vis Sci 1980, 19: 313–15.

    CAS  PubMed  Google Scholar 

  9. Hu C, Merolo LO, Kuwabara T, Kinoshita JH : Invest Ophthalmol Vis Sci 1984, 25: 603–5.

  10. Stribling D, Mirrlees DJ, Harrison HE, Earl DCN : Properties of IC128,436 a novel aldose reductase inhibitor and its effect on diabetic complications in the rat. Metabolism 1985, 34: 336–44.

    CAS  Article  Google Scholar 

  11. Ross WM, Creighton MO, Trevithick JR : Modelling cortical cataractogenesis: 3. In vivo effects of vitamin E on cataractogenesis in diabetic rats. Canad J Ophthalmol 1982, 17: 61–6.

    CAS  Google Scholar 

  12. Crompton M, Rixon KC, Harding JJ : Aspirin prevents carbamylation of soluble lens proteins and prevents cyanate-induced phase separation opacities. In-vitro. A possible mechanism by which aspirin could prevent cataract. Exp Eye Res 1985, 40: 297–311.

    CAS  Article  Google Scholar 

  13. Lewis BS, Rixon KK, Harding JJ : Bendazac prevents cyanate binding to soluble lens proteins and cyanate induced phase separation opacities in vitro: A possible mechanism by which Bendazac could delay cataract. Exp Eye Res 1986, 43: 973–9.

    CAS  Article  Google Scholar 

  14. Blondin J, Baragi V, Schwartz ER, Sadowski JA, Taylor A : Dietary vitamin C prevents eye lens protein damage. Invest Ophthalmol Vis Sci (Suppl) 1986, 27: 9 (Abstr 14) .

    Google Scholar 

  15. Miyata A : Studies on the experimental dimtrophenol cataract. Acta Soc Ophthalmol Jpn 1968, 72: 2307–24.

    CAS  Google Scholar 

  16. Von Sallman L : Further efforts to influence x-ray cataract by chemical agents. Arch Ophthalmol 1952, 48: 276–91.

    Article  Google Scholar 

  17. Pirie A and Lajtha LG : Possible mechanism of cysteine protection against radiation cataract. Nature 1959, 184: 1125–7.

    CAS  Article  Google Scholar 

  18. Straub W, Graul EH, Ruther W et al.: Untersuchungen uber die Wirkung strahlenschutzender Substanzen am vorderer Augenabschnitt des Kaninchens nach der Einwirkung schneller Neutronen. Albrecht von Graefes Arch Ophthalmol 1966, 169: 1–11.

    CAS  Article  Google Scholar 

  19. Sedlovets IF, Kozlov UA, Popov VV : Protection of the lens of mice against ionizing radiation with mercamine disulfide. Nach Kokl Vyssh Shk Biol Nauki 1967, 10: 67–70.

    Google Scholar 

  20. Hanna C and O'Brien JE : Effect on AET on X-ray radiation cataracts. Arch Int Pharmacodyn 1963, 142: 198–205.

    CAS  PubMed  Google Scholar 

  21. Fedorenko BS, Kabachenko AN, Vainsthein et al.: Effect of taurine and vita-iodurol on the incidence of experimental radiation induced catar- acts. Vestn Oftalmol 1978a, 6: 67–9.

    Google Scholar 

  22. Fedorenko BS, Kabachenko AN, Jarcev EI et al.: Der Einfluss von Taurin auf die Dynamik der Entwicklung experimenteller Katarakte bei Tieren. Radiobiol Radiother 1978b, 19: 452–8.

    CAS  Google Scholar 

  23. Vodovozov AM and Glotova NM : Results of treating senile cataracts with taurine. Vestn Oftalmol 1981, 2: 44–5.

    Google Scholar 

  24. Kador PF : Overview of the current attempts toward the medical treatment of cataract. Ophthalmology 1983, 90: 352–64.

    CAS  Article  Google Scholar 

  25. Weigein E and Hockwin O : Bericht ueber eine zufalls verteilte kontrolliert klinische Studie mit Phakan/Phakolen. Klin monatsbl Augenheilkd (In press).

  26. Ichikawa H, Imaizumi K, Tazawa et al.: Effect of Tiopronin on senile cataracts. Ophthalmologica 1980, 180: 293–8.

    CAS  Article  Google Scholar 

  27. Murata T : The effect of I-hydroxy-5-oxo-5H-pyrido (3, 2, ) phenoxazine-3-carboxylic acid (Catalin) on senile cataracts. Folia Ophthalmol Jpn 1980, 31: 1217–22.

    Google Scholar 

  28. Ogino S : Studies on the metabolism of crystalline lens. Acta Soc Ophthalmol Jpn 1955, 59: 666–710.

    Google Scholar 

  29. MacLean HA : A controlled trial of Catalin in senile cortical cataract. Concilium Ophthalmologicum 23rd, 1978. Kyoto (1979) 2: 1357–61.

    Google Scholar 

  30. Bonomi L, Marchini G, de Franco I, Perfetti S, de Gregorio M : Bendazac lysine salt in treatment of cataracts: A controlled study. Therapeutic Research 1983, 33: 768–82.

    Google Scholar 

  31. Mannucci LL, Doro D, Angi MR et al.: Treatment of presenile and senile cataract. Clinical evaluation of Bendazac lysine by means of a double-blind multicentre study. Boll di Oculistica 1983, 62: 87–94.

    Google Scholar 

  32. Testa M, Iuliano G, de Gregorio M, Pioggia M : A controlled clinical study of Bendzac lysine salt treatment in senile cataract. Acta Therapeutica 1983, 10: 177–90.

    Google Scholar 

  33. Cvintal T and Violante A : Double masked clinical trial of bendazac-lysine in senile patients. 25th International Congress of Ophthalmology, Rome, May 1986. (In press.)

  34. Harding JJ and van Heyningen R : Epidemiology and risk factors for cataract. Eye 1987, 1: 537–541.

    Article  Google Scholar 

  35. Brownlee M and Cerami A : The biochemistry of the complications of diabetes mellitus. Ann Rev Biochem 1981, 50: 385–432.

    CAS  Article  Google Scholar 

  36. Brown NAP, Bron AJ, Ayliffe W, Sparrow J, Hill AR : The objective assessment of cataract. Eye 1987, 1: 234–46.

    Article  Google Scholar 

Download references

Author information

Affiliations

  1. Oxford

    A J Bron, N A P Brown, J M Sparrow & G A Shun-Shin

Authors
  1. A J Bron
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N A P Brown
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J M Sparrow
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G A Shun-Shin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Presented at the Annual Congress of the Ophthalmological Society of the United Kingdom, April 1987.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Bron, A., Brown, N., Sparrow, J. et al. Medical treatment of cataract. Eye 1, 542–550 (1987). https://doi.org/10.1038/eye.1987.83

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/eye.1987.83

Further reading

Search

Advanced search

Quick links