Table 1: MSC and CFU-F concentrations and frequency derived from adult and near-fetal tissues

From: Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

Human tissue sourceNative CFU-F concentration range per ml of fluid/tissueMSC frequency range (CFU-F/106 nucleated cells)References
Bone marrow aspirate109–664a10–8391, 183, 184, 185, 186, 187
Adipose/lipoaspirate2058–9650205–51 00098, 184, 188, 189, 190
DermisNot reported74 000–157 00089
Umbilical cord blood0.060–0.02184, 185, 191, 192
Peripheral blood00–2b185, 192, 193
Synovial fluid4–142–25092, 194
Amniotic fluid39.2195
  1. aBased on average of 8 × 106 nucleated cells per ml bone marrow aspirate.183
  2. bOccurance of CFU-F in peripheral blood requires systemic treatment with GCSF.