Table 2 Summary of case–control counts in each cohort for alternative imbalance scenarios considered in the simulation study

From: Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes

Cohort No imbalance Moderate imbalance Extreme imbalance
  Cases Controls Cases Controls Cases Controls
1 1000 1000 600 1400 100 1900
2 1000 1000 700 1300 300 1700
3 1000 1000 800 1200 500 1500
4 1000 1000 900 1100 700 1300
5 1000 1000 1000 1000 900 1100
6 1000 1000 1000 1000 1100 900
7 1000 1000 1100 900 1300 700
8 1000 1000 1200 800 1500 500
9 1000 1000 1300 700 1700 300
10 1000 1000 1400 600 1900 100
Total 10 000 10 000 10 000 10 000 10 000 10 000