Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Short Communication
  • Published:

Habitual dietary phosphorus intake and urinary excretion in chronic kidney disease patients: a 3-day observational study

Abstract

Hyperphosphatemia in chronic kidney disease (CKD) is associated with vascular calcification, cardiovascular morbidity and mortality. The aim of this study was to estimate the daily dietary phosphorus intake compared with recommendations in CKD patients and to evaluate the reproducibility of the 24-h urinary phosphorus excretion. Twenty CKD patients stage 3–4 from the outpatient clinic, collected 24-h urine and kept dietary records for 3 consecutive days. The mean daily phosphorus intake was 1367±499, 1642±815 and 1426±706 mg/day, respectively (P=0.57). The mean urinary phosphorus excretion was 914±465, 954±414 and 994±479 mg/day, respectively (P=0.21). In this population of CKD patients stage 3–4 the daily phosphorus intake was above the recommended. Twenty-four-hour urinary phosphorus excretion was reproducible and the data indicate that a single 24-h urine collection is sufficient to estimate the individual phosphorus excretion.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu C . Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296–1305.

    Article  CAS  Google Scholar 

  2. Westerberg P-A, Linde T, Wikström B, Ljunggren O, Stridsberg M, Larsson TE . Regulation of fibroblast growth factor-23 in chronic kidney disease. Nephrol Dial Transplant 2007; 22: 3202–3207.

    Article  CAS  Google Scholar 

  3. Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD). Kidney Int Suppl 2009; 113: S1–130.

    Google Scholar 

  4. Kalantar-Zadeh K, Gutekunst L, Mehrotra R, Kovesdy CP, Bross R, Shinaberger CS et al. Understanding sources of dietary phosphorus in the treatment of patients with chronic kidney disease. Clin J Am Soc Nephrol 2010; 5: 519–530.

    Article  CAS  Google Scholar 

  5. Morimoto Y, Sakuma M, Ohta H, Suzuki A, Matsushita A, Umeda M et al. Estimate of dietary phosphorus intake using 24-h urine collection. J Clin Biochem Nutr 2014; 55: 62–66.

    Article  CAS  Google Scholar 

  6. Pedersen AN, Fagt S, Groth MV, Christensen T, Biltoft-Jensen A, Matthiessen J et al. Dietary habits in Denmark 2003-2008. Division of Nutrition, National Food Institute: Søborg, Denmark 2010.

  7. Uribarri J . Phosphorus additives in food and their effect in dialysis patients. Clin J Am Soc Nephrol 2009; 4: 1290–1292.

    Article  Google Scholar 

  8. Benini O, D’Alessandro C, Gianfaldoni D, Cupisti A . Extra-phosphate load from food additives in commonly eaten foods: a real and insidious danger for renal patients. J Ren Nutr 2011; 21: 303–308.

    Article  CAS  Google Scholar 

  9. Kalantar-Zadeh K, Moore LW, Tortorici AR, Chou JA, St-Jules DE, Aoun A et al. North American experience with Low protein diet for Non-dialysis-dependent chronic kidney disease. BMC Nephrol 2016; 17: 90.

    Article  Google Scholar 

  10. Heymsfield SB, Arteaga C, McManus C, Smith J, Moffitt S . Measurement of muscle mass in humans: validity of the 24-hour urinary creatinine method. Am J Clin Nutr 1983; 37: 478–94.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L Salomo.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Additional information

Author contributions

LS, MR and AK designed the research. LS, GMP and AK conducted the research. All authors analyzed and interpreted the data. LS and MR wrote the paper and had primary responsibility for final content. All authors contributed to the revision and final approval of the paper.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Salomo, L., Kamper, AL., Poulsen, G. et al. Habitual dietary phosphorus intake and urinary excretion in chronic kidney disease patients: a 3-day observational study. Eur J Clin Nutr 71, 798–800 (2017). https://doi.org/10.1038/ejcn.2016.247

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ejcn.2016.247

Search

Quick links