Table 4 Assessment of functional performance and ratings of perceived exertion at baseline and at the end of the intervention perioda

From: Double-blind, placebo-controlled pilot trial of L-Leucine-enriched amino-acid mixtures on body composition and physical performance in men and women aged 65–75 years

Functional performance variables Group A (n=8) Group B (n=8) Group C (n=9)
  Baseline Week 12 % ES Baseline Week 12 % ES Baseline Week 12 %
30-ACT (no) 14.6±4.7 16.3±4.0 15.0±20.0 0.8 17.4±4.0 18.6±3.6 8.3±13.7 0.6 18.6±3.0 18.7±3.0 0.9±11.2
30-CST (no) 11.6±3.9b 12.8±3.9b,c 11.0±11.5 0.5 14.1±2.0 15.9±3.2 13.2±16.0 0.5 16.4±2.1 17.1±2.3 4.7±15.7
Relative HST (N/(kg.bw)) 2.8±0.9 3.0±1.0 11.5±23.9 0.6 3.8±1.2 3.9±1.3 4.8±7.5 0.6 4.0±1.4 3.9±1.3 −0.2±8.9
6-WT (m) 501.6±101.1 539.0±83.0c 8.8±10.0 0.9 533.9±81.0 562.1±72.4c 5.8±6.6 0.7 586.0±85.0 593.0±82.1 1.4±4.5
Average RPE 11.3±1.7 11.0±1.5 −2.0±9.0b 1.3 11.7±1.0 11.1±1.6 −5.2±10.1 1.0 13.1±1.6 11.3±1.6c −13.7±5.1
  1. Abbreviations: A, standard essential amino-acid mixture (EAAs); B, EAAs containing 40% leucine; C, placebo; ES, Effect Size; HST, handgrip strength test; no, number of repetitions; RPE, rating of perceived exertion; %, mean percentage change from baseline to week 12; 30-CST, 30-s chair-stand test; 30-ACT, 30-s arm-curl test; 6-WT, 6-min walk test.
  2. aAll values are means±standard deviations.
  3. bDenotes significantly different from placebo (P<0.05) ME= mean of the experimental group, MP=mean of the placebo group. ES Cohen’s d =(ME-MP)/SD pooled).
  4. cDenotes significantly different from baseline value (P<0.05).