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Maternal nutrition, infants and children

Comparison of the fatty acid composition of transitional and mature milk of mothers who delivered healthy full-term babies, preterm babies and full-term small for gestational age infants

European Journal of Clinical Nutrition volume 67, pages 966–971 (2013)Cite this article

Subjects

Abstract

Background/objectives:

The fatty acid (FA) composition of breast milk throughout the period of lactation is fairly well understood. What is not known, however, is the FA composition of breast milk at the interface of physiology and pathology of pregnancy. We therefore decided to analyse and compare the differences in the FA composition of transitional and mature milk of mothers who delivered small for gestational age (SGA) neonates born at term; infants delivered at 35–37 weeks of gestation, that is ‘late preterm’; and that of mothers who gave birth to appropriate for gestational age neonates (AGA).

Subject/methods:

The FAs were analysed by HPLC equipped with MS detector.

Results:

We found differences in the percentage share of the studied FA pool regarding levels of capric, lauric and gadoleic acids. Comparing transitional and mature milk, the greatest diversity was seen in the group of mothers of AGA neonates and the least was noted in the group of mothers of SGA neonates.

Conclusions:

Both ‘late prematurity’ and reduced neonatal weight of children born at term affect the FA composition of breast milk. Even a small degree of fetal malformation alters the composition of breast milk, which is probably related to the child’s needs and condition.

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Acknowledgements

The authors gratefully acknowledge the Nutricia Foundation. The study was supported by grant number RG3/2006.

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Authors and Affiliations

  1. Faculty of Health Sciences, University of Bielsko-Biala, Bielsko-Biała, Poland

    R Bobiński & M Mikulska

  2. Chemical Safety of Food Laboratory, National Food and Nutrition Institute, Warsaw, Poland

    H Mojska

  3. Department of Neonatology, Provincial Specialist Hospital, Tychy, Poland

    M Simon

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  1. R Bobiński
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  2. M Mikulska
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  4. M Simon
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Correspondence to R Bobiński.

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Bobiński, R., Mikulska, M., Mojska, H. et al. Comparison of the fatty acid composition of transitional and mature milk of mothers who delivered healthy full-term babies, preterm babies and full-term small for gestational age infants. Eur J Clin Nutr 67, 966–971 (2013). https://doi.org/10.1038/ejcn.2013.96

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