Table 3 Meta-regression models investigating effect of amount of coffee and study duration on TC, LDL-C and TG

From: The effect of coffee consumption on serum lipids: a meta-analysis of randomized controlled trials

  TC LDL-C TG
  Coefficient (95% Cl) P Coefficient (95% Cl) P Coefficient (95% Cl) P
Cups of coffee
 Model Ia 3.59 (1.05, 6.14) 0.008 3.11 (0.51, 5.71) 0.023 6.23 (2.33, 10.13) 0.005
 Model IIb 3.74 (1.21, 6.27) 0.006 3.38 (1.17, 5.60) 0.006 6.56 (3.02, 10.11) 0.003
Duration (week)
 Model Ia 0.11 (−1.90, 2.12) 0.911 −0.41 (−2.88, 2.05) 0.720 −1.20 (−4.75, 2.34) 0.462
 Model IIc 1.76 (−0.01, 3.53) 0.051 0.63 (−1.19, 2.46) 0.460 0.94 (−1.43, 3.31) 0.378
  1. Abbreviations: CI, confidence interval; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.
  2. aUnadjusted model.
  3. bAdjusted for coffee brewing method (filtered or unfiltered) and study duration.
  4. cAdjusted for coffee brewing method (filtered or unfiltered) and cups of coffee.