Table 4 Sex-specific multivariable hazard ratios (HRs) and 95% confidence intervals (95% CIs) of mortality from ischemic heart disease according to quintiles of total meat consumption stratified by body mass index (BMI)

From: Meat consumption in relation to mortality from cardiovascular disease among Japanese men and women

  Quintile of total meat consumption P for trenda
  Q1 (low) Q2 Q3 Q4 Q5 (high)  
  reference HR 95% CI HR 95% CI HR 95% CI HR 95% CI  
Men
BMI <25 kg/m2
Person-years 50 578 52 764 52 929 53 123 51 803  
No. of subjects 3339 3384 3360 3379 3389  
No. of cases 49 56 51 36 40  
Multivariable HRb 1.00 1.23 (0.83–1.82) 1.12 (0.75–1.68) 0.78 (0.50–1.21) 0.75 (0.48–1.18) 0.048
BMI 25 kg/m2
Person-years 12 082 11 543 11 832 11 282 11 151  
No. of subjects 754 709 734 714 704  
No. of cases 25 9 12 13 10  
Multivariable HRb 1.00 0.39 (0.18–0.86) 0.52 (0.25–1.09) 0.61 (0.30–1.25) 0.36 (0.15–0.83) 0.043
Women
BMI <25 kg/m2
Person-years 76 124 78 615 79 825 80 296 79 673  
No. of subjects 4826 4905 4953 4990 4965  
No. of cases 56 35 33 29 25  
Multivariable HRb 1.00 0.99 (0.64–1.53) 1.07 (0.68–1.67) 0.98 (0.61–1.57) 0.87 (0.52–1.45) 0.623
BMI 25 kg/m2
Person-years 22 733 21 577 21 093 20 293 20 761  
No. of subjects 1417 1339 1290 1254 1278  
No. of cases 17 9 6 6 20  
Multivariable HRb 1.00 0.64 (0.27–1.47) 0.58 (0.22–1.53) 0.53 (0.20–1.40) 2.04 (0.98–4.26) 0.040
  1. aOn the basis of the tests for trend across quintiles of meat consumption by assigning the median value of each quintile.
  2. bCox proportional hazard models adjusted for the same variables shown in the footnote of Table 2.