Table 3 Sex-specific multivariable hazard ratios (HRs) and 95% confidence intervals (95% CIs) of mortality from ischemic heart disease according to quintiles of each meat consumptions (energy adjusted)

From: Meat consumption in relation to mortality from cardiovascular disease among Japanese men and women

  Quintile of each meat consumptions P for trenda
  Q1 (low) Q2 Q3 Q4 Q5 (high  
  reference HR 95% CI HR 95% CI HR 95% CI HR 95% CI  
Men (n) 4093 4093 4094 4093 4093  
Red meat
Median consumption (g/day) 6.4 15.5 23.3 33.2 57.8  
Person-years 62 785 64 247 64 694 64 366 62 995  
No. of cases 69 74 53 59 46  
Multivariable HRb 1.00 1.19 (0.85-1.65) 0.88 (0.61–1.27) 1.00 (0.70–1.44) 0.7 (0.47–1.04) 0.038
Poultry
Median consumption (g/day) 1.9 3.3 10.2 13.3 27.3  
Person-years 63 758 62 452 65 983 64 031 62 863  
No. of cases 67 68 51 49 66  
Multivariable HRb 1.00 0.85 (0.58–1.25) 0.93 (0.63–1.37) 0.63 (0.41–0.96) 0.86 (0.60–1.23) 0.405
Processed meat
Median consumption (g/day) 1.2 1.5 2.9 6.1 13.9  
Person-years 64 599 62 210 61 509 66 035 64 734  
No. of cases 62 72 74 50 43  
Multivariable HRb 1.00 1.01 (0.66–1.54) 0.87 (0.55–1.37) 0.80 (0.53–1.21) 0.56 (0.36–0.88) 0.002
Liver
Median consumption (g/day) 1.2 1.5 2.7 3.6 15.2  
Person-years 66 472 62 899 64 653 63 822 61 240  
No. of cases 56 74 63 42 66  
Multivariable HRb 1.00 0.95 (0.61–1.48) 1.02 (0.69–1.51) 0.72 (0.46–1.15) 0.95 (0.63–1.42) 0.838
Women (n) 6243 6244 6243 6244 6243  
Red meat
Median consumption (g/day) 4.0 11.5 17.8 25.5 43.9  
Person-years 989 01 100 792 101 160 100 591 99 544  
No. of cases 77 47 30 38 44  
Multivariable HRb 1.00 0.96 (0.66–1.40) 0.71 (0.46–1.10) 1.02 (0.68–1.54) 1.23 (0.82–1.85) 0.317
Poultry
Median consumption (g/day) 1.5 4.2 8.6 11.3 22.4  
Person–years 99 439 98 542 102 799 99 074 101 134  
No. of cases 48 55 40 50 43  
Multivariable HRb 1.00 1.09 (0.72–1.66) 1.24 (0.78–1.98) 1.12 (0.72–1.74) 1.06 (0.69–1.62) 0.888
Processed meat       
Median consumption (g/day) 0.9 1.2 2.2 4.7 10.4  
Person-years 100 156 97 701 97896 103 346 101 890  
No. of cases 44 60 63 32 37  
Multivariable HRb 1.00 1.12 (0.68–1.84) 1.04 (0.61–1.84) 0.92 (0.56–1.50) 0.98 (0.59–1.62) 0.631
Liver
Median consumption (g/day) 0.9 1.0 1.6 2.3 11.1  
Person-years 103 829 100 394 98 706 100 520 97 540  
No. of cases 42 54 55 31 54  
Multivariable HRb 1.00 0.91 (0.50–1.67) 0.66 (0.37–1.19) 0.88 (0.51–1.51) 1.01 (0.60–1.68) 0.166
  1. aOn the basis of the tests for trend across quintiles of meat consumption by assigning the median value of each quintile.
  2. bCox proportional hazard models adjusted for the same variables shown in the footnote of Table 2.