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Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial

Abstract

Background/Objectives:

Hypoglycemic effect of camel milk supplementation in experimental rat model and significant reduction in doses of insulin in type 1 diabetic patients have been observed in our previous studies. This long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an adjunct to insulin therapy in type 1 diabetics.

Subjects/Methods:

In this 2-year randomized clinical, parallel design study, 24 type 1 diabetics were enrolled and divided into two groups. Group I (n=12) received usual care, that is, diet, exercise and insulin and Group II (n=12) received 500 ml camel milk in addition to the usual care. Insulin requirement was titrated weekly by blood glucose estimation. Results were analyzed by using the regression technique.

Results:

In camel milk group, there was decrease in mean blood glucose (118.58±19–93.16±17.06 mg/dl), hemoglobin A1c levels (7.81±1.39–5.44±0.81%) and insulin doses (32.50±9.99–17.50±12.09 U/day, P<0.05). Out of 12 subjects receiving camel milk, insulin requirement in 3 subjects reduced to zero. There was nonsignificant change in plasma insulin and anti-insulin antibodies in both the groups.

Conclusion:

It may be stated that camel milk is safe and efficacious in improving long-term glycemic control, with a significant reduction in the doses of insulin in type 1 diabetic patients.

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Correspondence to R P Agrawal.

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Agrawal, R., Jain, S., Shah, S. et al. Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial. Eur J Clin Nutr 65, 1048–1052 (2011). https://doi.org/10.1038/ejcn.2011.98

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  • DOI: https://doi.org/10.1038/ejcn.2011.98

Keywords

  • camel milk
  • diabetes
  • adjunctive therapy
  • glycemic control
  • insulin therapy

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