Table 2 Changes in vital signs and in brachial artery flow-mediated dilation after ingestion of caffeinated or decaffeinated espresso coffeea

From: Acute effects of coffee on endothelial function in healthy subjects

  Coffee P-valueb
  Caffeinated (N=20) Decaffeinated (N=20) Time Time × treatment
Systolic blood pressure (mm Hg)
 Basal 113±2 112±2   
 30 min 116±2* 111±2 0.75 0.22
 60 min 116±2* 111±2   
P-valuec 0.003 0.22   
Diastolic blood pressure (mm Hg)
 Basal 68±2 66±2   
 30 min 72±2* 68±2 0.30 0.27
 60 min 72±2* 67±2   
P-valuec 0.001 0.07   
Heart rate (beats/min)
 Basal 68±2 69±2   
 30 min 69±2 69±1 <0.01 0.63
 60 min 67±2 68±2   
P-valuec 0.27 0.08   
Flow-mediated dilation (%)
 Basal 7.7±0.6 6.9±0.6   
 30 min 6.3±0.7 8.1±0.9 0.98 <0.005
 60 min 6.0±0.8* 8.5±0.9   
P-valuec 0.04 0.12   
  1. Abbreviation: ANOVA, analysis of variance.
  2. aAll values are mean±s.e.m.
  3. b3 × 2 ANOVA for repeated measures.
  4. cP-value compares within group values between basal, 30 min and 60 min for each variable within each group.
  5. Paired t-test: *P< 0.05 vs both decaffeinated coffee and basal value.