Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Short Communication
  • Published:

Celiac disease and obesity: need for nutritional follow-up after diagnosis

Abstract

More than 20 years of serological approach to diagnosis of celiac disease (CD) has deeply changed the classical clinical presentation of the disease, and some reports indicate that CD and obesity can coexist in both childhood and adolescence. We reviewed clinical records of 149 children with CD followed in our institution between 1991 and 2007, considering weight, height and body mass index (BMI), both at diagnosis and after at least 12 months of gluten-free diet (GFD). In all, 11% of patients had BMI z-score >+1 and 3% were obese (z-score >+2) at presentation. In our population, there was a significant (P=0.008) increase in BMI z-score after GFD and the percentage of overweight (z-score >+1) subjects almost doubled (11 vs 21%, P=0.03). Our data suggest the need for a careful follow-up of nutritional status after diagnosis of CD, especially addressing those who are already overweight at presentation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Similar content being viewed by others

References

  • Arslan N, Esen I, Demircioglu F, Yilmaz S, Unuvar T, Bober E (2009). The changing face of celiac disease: a girl with obesity and celiac disease. J Paediatr Child Health 45, 317–318.

    Article  Google Scholar 

  • Dickey W, Kearney N (2006). Overweight in celiac disease: prevalence, clinical characteristics, and effect of a gluten-free diet. Am J Gastroenterol 101, 2356–2359.

    Article  CAS  Google Scholar 

  • Ferrara P, Cicala M, Tiberi E, Spadaccio C, Marcella L, Gatto A et al. (2009). High fat consumption in children with celiac disease. Acta Gastroenterol Belg 72, 296–300.

    CAS  PubMed  Google Scholar 

  • Franzese A, Iannucci MP, Valerio G, Ciccimarra E, Spaziano M, Mandato C et al. (2001). Atypical celiac disease presenting as obesity-related liver dysfunction. J Pediatr Gastroenterol Nutr 33, 329–332.

    Article  CAS  Google Scholar 

  • Hopman EGD, le Cessie S, von Blomberg ME, Mearin ML (2006). Nutritional management of the gluten-free diet in young people with celiac disease in The Netherlands. J Pediatr Gastroenterol Nutr 43, 102–108.

    Article  CAS  Google Scholar 

  • Mariani P, Viti MG, Montouri M, La Vecchia A, Cipolletta E, Calvani L et al. (1998). The gluten-free diet: a nutritional risk factor for adolescents with celiac disease? J Pediatr Gastroenterol Nutr 27, 19–23.

    Article  Google Scholar 

  • Marsh MN (1990). Grains of truth: evolutionary changes in small intestinal mucosa in response to environmental antigen challenge. Gut 31, 111–114.

    Article  CAS  Google Scholar 

  • Conti-Nibali S, MagazzĂą G, De Luca F (1987). Obesity in a child with untreated celiac disease. Helv Paediatr Acta 42, 45–48.

    CAS  PubMed  Google Scholar 

  • Oso O, Fraser NC (2006). A boy with coeliac disease and obesity. Acta Paediatr 95, 618–619.

    Article  Google Scholar 

  • Telega G, Bennet TR, Werlin S (2008). Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med 162, 164–168.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to E Valletta.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Valletta, E., Fornaro, M., Cipolli, M. et al. Celiac disease and obesity: need for nutritional follow-up after diagnosis. Eur J Clin Nutr 64, 1371–1372 (2010). https://doi.org/10.1038/ejcn.2010.161

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ejcn.2010.161

Keywords

This article is cited by

Search

Quick links