Metagenome-assembled genomes provide unprecedented characterization of human-associated microbiota

Credit: N. Wallington / Springer Nature Limited

Advances in computational methods, recently pioneered in the environmental microbiology field, enable the reconstruction of bacterial genomes from metagenomic datasets. This approach was used to identify thousands of new uncultured candidate bacterial species from the gut and other body sites, of global populations from rural and urban settings, substantially expanding the known phylogenetic diversity and improving classification of understudied, non-Western populations.

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