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An aerial view of the excavations and construction work on the Orion site.

The construction site of the maximum-level biosafety laboratory Orion lies next to a circular synchrotron facility at the Brazilian Center for Research in Energy and Materials in Campinas.Credit: Disclosure/CNPEM

First max-security South American biolab

Last month, Brazil broke ground on the first maximum-security biosciences laboratory in Latin America. Many researchers are excited at the prospect of a biosafety-level-4 (BSL-4) facility where they can safely study the most dangerous pathogens in the region. However, some wonder about the cost of maintaining such a lab and are concerned about the pushback they might receive from the public over housing deadly organisms there.

Nature | 6 min read

Why Canada burned

Hotter than average temperatures, earlier than average snowmelt and lower than average rainfall, all spurred by climate change, led to last summer’s devastating wildfires in Canada. In 2023, fires burned 150,000 square kilometres — seven times the historical average and roughly 4% of Canada’s forest. More than 200 communities were evacuated and hazardous smoke travelled as far as Europe. Fires in the west were worsened by years of drought, while eastern Canada experienced a sudden ‘flash drought’: “an emerging phenomenon that we are only beginning to understand”, write researchers.

CTV News | 4 min read

Reference: Nature Communications paper or read the Nature Research Highlight (2 min read, Nature paywall)

Spider makes fireflies flash as bait

Orb-weaving spiders (Araneus ventricosus) make trapped male Absocondita terminalis fireflies flash like females to tempt more insects into their web. The spiders bite and wrap a flashing male firefly using a different technique than the one used on other prey. This method seems to change the repeating light sequence of the male firefly — which can still flash after being bitten — to one that resembles a female’s single pulse. The signal seems to tempt more males to their demise.

Science | 5 min read

Reference: Current Biology paper or read the Nature Research Highlight (2 min read, Nature paywall)

Features & opinion

How to road-test medical AI

People developing artificial-intelligence (AI) systems for use in medical settings aim to save lives — but the testing required to verify that these systems are working isn’t always happening. Only a small proportion of devices — those that might pose a high risk to patients — require clinical-trial data for approval, and few such trials have been published. Researchers know what an ideal clinical trial for an AI-based intervention should look like, but in practice, testing these technologies is challenging — it’s not even clear how to best inform patients and ask for their consent.

Nature | 11 min read

Midwife became neuroscientist to save son

Terry Jo Bichell became a PhD student in her fifties to train as a neuroscientist. Her goal: investigate treatments for Angelman syndrome, a rare developmental disorder that affects her son. It wasn’t her first career pivot — she was working as a documentary film-maker when she witnessed the tragic end to a difficult birth; the experience inspired her to become a midwife. After her PhD, Bichell took another less-trodden path: she founded COMBINEDBrain, a non-profit that connects patient advocates with scientists. “She’s a bridge-builder,” says her former supervisor, neuroscientist Aaron Bowman.

Nature | 9 min read

Image of the week

A frog with blue glowing eyes sitting on a green bioluminescent mushroom

Credit: Toby Schrapel

This little frog and the mushroom it sits on are both naturally luminous. The frog’s blue eyes are an example of biofluorescence — when an organism has a chemical surface that absorbs light at one wavelength and re-emits it at another. By contrast, the mushroom’s green glow is generated by a reaction in its cells. The scene, captured by photographer Toby Schrapel, is a finalist in the Beaker Street Science Photography Prize.

See more of last month’s sharpest science shots, selected by Nature’s photo team.

QUOTE OF THE DAY

“The brain changes in its needs moment to moment, hour to hour, week to week.”

Neurologist Philip Starr and his colleagues designed a brain implant that applies deep-brain stimulation to treat the symptoms of Parkinson’s disease in a personalized way. (The New York Times | 7 min read)

Reference: Nature Medicine paper