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Major AlphaFold upgrade offers boost for drug discovery

Latest version of the AI models how proteins interact with other molecules — but DeepMind restricts access to the tool.
  1. Ewen Callaway
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Since the powerhouse artificial intelligence (AI) tool AlphaFold2 was released in 2021, scientists have used the protein-structure-prediction model to map one of our cells’ biggest machines, discover drugs and chart the universe of every known protein.

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Nature 629, 509-510 (2024)

doi: https://doi.org/10.1038/d41586-024-01383-z

References

  1. Abramson, J. et al. Nature https://doi.org/10.1038/s41586-024-07487-w (2024).

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  2. Jumper, J. et al. Nature 596, 583–589 (2021).

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  3. Senior, A. W. et al. Nature 577, 706–710 (2020).

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  4. Krisha, R. et al. Science https://doi.org/10.1126/science.adl2528 (2024).

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