Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Why is exercise good for you? Scientists are finding answers in our cells

Thousands of swimmers race 6.5 kilometres from Kanlıca to Kuruçeşme in Istanbul in 2023.

Researchers are looking into the molecular basis of how exercise benefits health, to help treat diseases. Credit: Ozan Guzelce/dia images via Getty

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Nature 629, 26-28 (2024)

doi: https://doi.org/10.1038/d41586-024-01200-7

Updates & Corrections

  • Correction 07 May 2024: An earlier version of this News feature gave an old affiliation for Bret Goodpaster. He is now at AdventHealth Research Institute in Orlando, Florida.

References

  1. Moore, S. C. et al. PLoS Med. 9, e1001335 (2012).

    Article  PubMed  Google Scholar 

  2. MoTrPAC Study Group. Nature 629, 174–183 (2024).

    Article  Google Scholar 

  3. Many, G. M. et al. Nature Metab. https://doi.org/10.1038/s42255-023-00959-9 (2024).

    Article  Google Scholar 

  4. Vetr, N. G. et al. Nature Commun. https://doi.org/10.1038/s41467-024-45966-w (2024).

    Article  Google Scholar 

  5. Ransom, F. J. Physiol. 40, 1–16 (1910).

    Article  PubMed  Google Scholar 

  6. Goldstein, M. S. Diabetes 10, 232–234 (1961).

    Article  Google Scholar 

  7. Ostrowski, K., Rohde, T., Asp, S., Schjerling, P. & Pedersen, B. K. J. Physiol. 515, 287–291 (1999).

    Article  PubMed  Google Scholar 

  8. Steensberg, A., van Hall, G., Osada, T., Sacchetti, M., Saltin, B. & Klarlund Pedersen, B. J. Physiol. 529, 237–242 (2000).

    Article  PubMed  Google Scholar 

  9. Contrepolis, K. et al. Cell 181, 1112–1130 (2020).

    Article  PubMed  Google Scholar 

  10. Wei, W. et al. Cell Metab. 35, 1261–1279 (2023).

    Article  PubMed  Google Scholar 

  11. Whitham, M. et al. Cell Metab. 27, 237–251 (2018).

    Article  PubMed  Google Scholar 

  12. Billon, C. et al. ACS Chem. Biol. 18, 756–771 (2023).

    Article  PubMed  Google Scholar 

  13. Billon, C. et al. J. Pharmacol. Exp. Ther. 388, 232–240 (2024).

    Article  PubMed  Google Scholar 

  14. Kurz, E. et al. Cancer Cell 40, 720–737 (2022).

    Article  PubMed  Google Scholar 

Download references

Subjects

Latest on:

Nature Careers

Jobs

  • Postdoctoral Associate- Neuroscience

    Houston, Texas (US)

    Baylor College of Medicine (BCM)

  • Chief Editor, Nature Materials

    Job Title:  Chief Editor, Nature Materials Location: New York, Shanghai or Beijing Closing date: Sept 2, 2024   Springer Nature, the publisher of N...

    New York City, New York (US)

    Springer Nature Ltd

  • Tenure Track Assistant or Associate Professor

    Frontotemporal Dementia Research Center seeking highly motivated creative and collaborative scientist in RNA Biology to enhance our understanding.

    Worcester, Massachusetts

    UMass Chan Medical School

  • Department Head - Biomedical Engineering

    VT BEAM seeks a Department Head to lead its innovative multidisciplinary approach bridging biomedical science with practical applications.

    Blacksburg, Virginia

    Virginia Tech- Biomedical Engineering

  • Postdoctoral Research Scientist

    Postdoctoral Research Scientist in the Department of Pediatrics

    New York City, New York (US)

    Columbia University Irving Medical Center- Department of Pediatrics

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links