Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • NEWS

How one man’s rare Alzheimer’s mutation delayed the onset of disease

Genetic resilience found in a person predisposed to early-onset dementia could potentially lead to new treatments.
  1. Sara Reardon
    View author publications

    You can also search for this author in PubMed  Google Scholar

Researchers have identified a man with a rare genetic mutation that protected him from developing dementia at an early age. The finding, published on 15 May in Nature Medicine1, could help researchers to better understand the causes of Alzheimer’s disease and potentially lead to new treatments.

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Nature 617, 660-661 (2023)

doi: https://doi.org/10.1038/d41586-023-01610-z

References

  1. Lopera, F. et al. Nature Med. https://doi.org/10.1038/s41591-023-02318-3 (2023).

    Article  Google Scholar 

  2. Arboleda-Velasquez, J. F. et al. Nature Med. 25, 1680–1683 (2019).

    Article  PubMed  Google Scholar 

Download references

Subjects

Latest on:

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Advanced search

Quick links