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How to halt an infectious yeast’s stealthy spread

Candida albicans, which causes oral thrush and other illnesses, stops sending out invasive tendrils when hit with a compound called H55.
Colour enhanced scanning electron micrograph (SEM) of the yeast-like fungus Candida albicans, a cause of thrush (candidiasis).

The fungus Candida albicans (artificially coloured) switches from a compact, rounded form to a filamentous form to invade host cells. Credit: Nano Creative/Science Source/SPL

A variation on a painkiller used to treat ear infections could protect people from pathogenic yeast1.

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Nature 617, 440 (2023)

doi: https://doi.org/10.1038/d41586-023-01543-7

References

  1. Jin, X. et al. Cell Chem. Biol. https://doi.org/10.1016/j.chembiol.2023.04.010 (2023).

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