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‘Remarkable’ AI tool designs mRNA vaccines that are more potent and stable

Software from Baidu Research yields jabs for COVID that have greater shelf stability and that trigger a larger antibody response in mice than conventionally designed shots.
  1. Elie Dolgin
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An artificial intelligence (AI) tool that optimizes the gene sequences found in mRNA vaccines could help to create jabs with greater potency and stability that could be deployed across the globe.

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doi: https://doi.org/10.1038/d41586-023-01487-y

References

  1. Zhang H. et al. Nature https://doi.org/10.1038/s41586-023-06127-z (2023).

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  2. Leppek, K. et al. Nature Commun. 13, 1536 (2022).

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