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Air pollution’s role in the promotion of lung cancer

Air pollution is associated with the development of lung cancer. Analysis of clinical samples and mouse cancer models suggests that inflammation and a tumour-promotion process induced by polluted air are the major culprits.
  1. Allan Balmain

    1. Allan Balmain is at the UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California 94158, USA.

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The mechanisms underlying how air pollution can contribute to lung cancer have been hard to pinpoint. Writing in Nature, Hill et al.1 report studies of human lung samples and mouse cancer models that shed light on this issue.

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Nature 616, 35-36 (2023)

doi: https://doi.org/10.1038/d41586-023-00929-x

References

  1. Hill, W. et al. Nature 616, 159–167 (2023).

    Article  Google Scholar 

  2. Cohen, A. J. et al. Lancet 389, 1907–1918 (2017).

    Article  PubMed  Google Scholar 

  3. Riva, L. et al. Nature Genet. 52, 1189–1197 (2020).

    Article  PubMed  Google Scholar 

  4. Fowler J. C. & Jones, P. H. Cancer Discov. 12, 1642–1655 (2022).

    Article  PubMed  Google Scholar 

  5. Berenblum, I. & Shubik, P. Br. J. Cancer 3, 384–386 (1949).

    Article  PubMed  Google Scholar 

  6. Quintanilla M., Brown K., Ramsden M. & Balmain A. Nature 322, 78–80 (1986).

    Article  PubMed  Google Scholar 

  7. Brown, K. et al. Cell 46, 447–456 (1986).

    Article  PubMed  Google Scholar 

  8. Hecker, E. Naturwissenschaften 54, 282–284 (1967).

    Article  PubMed  Google Scholar 

  9. Clemo, G. R. & Miller, E. W. Br. J. Cancer 14, 651–656 (1960).

    Article  PubMed  Google Scholar 

  10. Wynder, E. L. & Hoffman, D. J. Air Pollut. Control Assoc. 15, 155–159 (1965).

    Article  PubMed  Google Scholar 

  11. Balmain, A. Eur. J. Epidemiol. https://doi.org/10.1007/s10654-022-00933-x (2022).

    Article  Google Scholar 

  12. Ridker, P. M. et al. Lancet 390, 1833–1842 (2017).

    Article  PubMed  Google Scholar 

  13. Tremmel, L., Rho, O., Slaga, T. J. & DiGiovanni, J. Mol. Carcinogen. 58, 185–195 (2019).

    Article  Google Scholar 

  14. Omenn, G. S. Eur. J. Cancer Prev. 16, 184–191 (2007).

    Article  PubMed  Google Scholar 

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Competing Interests

The author declares no competing interests.

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