Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


How an anxious heart talks to the brain

Access options

Rent or buy this article

Get just this article for as long as you need it


Prices may be subject to local taxes which are calculated during checkout

Nature 615, 217-218 (2023)



  1. Paulus, M. P. & Stein, M. B. Brain Struct. Funct. 214, 451–463 (2010).

    Article  PubMed  Google Scholar 

  2. Cannon, W. B. Am. J. Psychol. 39, 106–124 (1927).

    Article  Google Scholar 

  3. Hsueh, B. et al. Nature 615, 292–299 (2023).

    Article  Google Scholar 

  4. Azzalini, D., Rebollo, I. & Tallon-Baudry, C. Trends Cogn. Sci. 23, 488–509 (2019).

    Article  PubMed  Google Scholar 

  5. Livneh, Y. & Andermann, M. L. Neuron 109, 3576–3593 (2021).

    Article  PubMed  Google Scholar 

  6. Klein, A. S., Dolensek, N., Weiand, C. & Gogolla, N. Science 374, 1010–1015 (2021).

    Article  PubMed  Google Scholar 

  7. Chen, R. et al. Nature Biotechnol. 39, 161–164 (2021).

    Article  PubMed  Google Scholar 

  8. Etkin, A. & Wager, T. D. Am. J. Psychiatry 164, 1476–1488 (2007).

    Article  PubMed  Google Scholar 

  9. Gehrlach, D. A. et al. Nature Neurosci. 22, 1424–1437 (2019).

    Article  PubMed  Google Scholar 

  10. Nicolas, C. et al. Preprint at Research Square (2021).

Download references

Competing Interests

The authors declare no competing interests.


Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing


Quick links