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How antidepressants help bacteria resist antibiotics

A laboratory study unravels ways non-antibiotic drugs can contribute to drug resistance.
  1. Liam Drew
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The emergence of disease-causing bacteria that are resistant to antibiotics is often attributed to the overuse of antibiotics in people and livestock. But researchers have homed in on another potential driver of resistance: antidepressants. By studying bacteria grown in the laboratory, a team has now tracked how antidepressants can trigger drug resistance1.

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doi: https://doi.org/10.1038/d41586-023-00186-y

References

  1. Wang, Y. et al. Proc. Natl Acad. Sci. USA 120, e2208344120 (2023).

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  2. Antimicrobial Resistance Collaborators Lancet 399, 629–655 (2022).

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  3. Jin, M. et al. Environ. Int. 120, 421–430 (2018).

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