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  • RESEARCH BRIEFINGS

A set of factors that silence the protein-making machinery in eggs

In egg cells, the ribosomes — the machinery responsible for protein synthesis — are stored in a dormant state that is released later in the developing embryo. An evolutionarily conserved set of proteins has been shown to bind to ribosomes in the egg cells of vertebrates, stabilizing the ribosomes and suppressing their activity.

This is a summary of: Leesch, F. et al. A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature https://doi.org/10.1038/s41586-022-05623-y (2023).

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doi: https://doi.org/10.1038/d41586-022-04526-2

‘Expert opinion’ is published under a CC BY 4.0 licence.

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