NEWS
05 October 2022

Chemists who invented revolutionary ‘click’ reactions win Nobel

Researchers honoured for game-changing methods to couple molecules, including reactions that can be run in living cells.

Davide Castelvecchi &
Heidi Ledford

Davide Castelvecchi

View author publications

You can also search for this author in PubMed Google Scholar
Heidi Ledford

View author publications

You can also search for this author in PubMed Google Scholar

Access through your institution

Buy or subscribe

Three chemists who pioneered a useful technique called click chemistry to join molecules together efficiently have won this year’s Nobel Prize in Chemistry.

Access options

Access through your institution

Rent or buy this article

Get just this article for as long as you need it

$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Nature 610, 242-243 (2022)

doi: https://doi.org/10.1038/d41586-022-03087-8

References

Kolb, H. C., Finn, M. G. & Sharpless, K. B. Angew. Chem. Int. Edn 40, 2004–2021 (2001).
Article Google Scholar
Tornøe, C. W. & Meldal, M. In Peptides 2001 Proc. Am. Pept. Symp. 263–264 (Kluwer Academic Publishers, 2001).
Google Scholar
Rostovtsev, V. V., Green, L. G., Fokin, V. V. & Sharpless, K. B. Angew. Chem. Int. Edn 41, 2596–2599 (2002).
Article Google Scholar
Agard, N. J., Prescher, J. A. & Bertozzi, C. R. J. Am. Chem. Soc. 126, 15046–15047 (2004).
Article PubMed Google Scholar
Wittig, G. & Krebs, A. Chem. Ber. 94, 3260–3275 (1961).
Article Google Scholar