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  • RESEARCH HIGHLIGHT

How do humans resist tuberculosis? With a metabolic protein’s help

A protein that boosts energy metabolism in immune cells might help to prevent tuberculosis infections taking hold.
Coloured scanning electron micrograph of a macrophage engulfing a tuberculosis-causing bacterium

The bacteria that cause tuberculosis (pink; artificially coloured) are engulfed by an immune cell called a macrophage. Credit: Science Photo Library

A key metabolic protein can shield immune cells from the bacterium that causes tuberculosis, according to a study in zebrafish and human cells1.

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Nature 609, 878 (2022)

doi: https://doi.org/10.1038/d41586-022-02987-z

References

  1. Pagán, A. J. et al. Cell https://doi.org/10.1016/j.cell.2022.08.018 (2022).

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