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  • RESEARCH HIGHLIGHT

A sugary diet wrecks gut microbes — and their anti-obesity efforts

A high-sugar diet unbalances the microbiome, so the body makes fewer of the gut immune cells that help to prevent metabolic disorders.
Shelves piled high with a variety of doughnuts for sale at a market.

A high-sugar diet encourages growth of gut bacteria that crowd out helpful microorganisms. Credit: Alena Kravchenko/EyeEm/Getty

An intricate relationship between diet, gut bacteria and immune cells helps to protect against obesity and other metabolic conditions, according to experiments in mice1.

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Nature 609, 445 (2022)

doi: https://doi.org/10.1038/d41586-022-02775-9

References

  1. Kawano, Y. et al. Cell https://doi.org/10.1016/j.cell.2022.08.005 (2022).

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