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  • RESEARCH HIGHLIGHT

Designer antiviral takes aim at one of influenza’s soft spots

Influenza A could have trouble mutating its way past a molecule that damages a crucial structure in the viral genome.
Coloured transmission electron micrograph of H3N2 influenza virus particles

Particles (artificially coloured) of influenza A, which did not have its usual lethal effect on mice treated with a new type of antiviral compound. Credit: CDC/SPL

Viruses such as influenza mutate so quickly that they can rapidly develop resistance to antiviral drugs. A new antiviral that targets an important structure in influenza’s genome might make it more difficult for the virus to become resistant1.

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Nature 609, 12 (2022)

doi: https://doi.org/10.1038/d41586-022-02282-x

References

  1. Hagey, R. J. et al. Nature Med. https://doi.org/10.1038/s41591-022-01908-x (2022).

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