Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • NEWS AND VIEWS

A short burst of reward curbs the addictiveness of ketamine

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Nature 608, 271-272 (2022)

doi: https://doi.org/10.1038/d41586-022-01948-w

References

  1. Krystal, J. H., Abdallah, C. G., Sanacora, G., Charney, D. S. & Duman, R. S. Neuron 101, 774–778 (2019).

    Article  PubMed  Google Scholar 

  2. Morgan, C. J. A., Curran, H. V. & the Independent Scientific Committee on Drugs (ISCD). Addiction 107, 27–38 (2012).

    Article  PubMed  Google Scholar 

  3. Simmler, L. D. et al. Nature 608, 368–373 (2022).

    Article  Google Scholar 

  4. Dayan, P. & Niv, Y. Curr. Opin. Neurobiol. 18, 185–196 (2008).

    Article  PubMed  Google Scholar 

  5. Saunders, B. T., Richard, J. M., Margolis, E. B. & Janak, P. H. Nature Neurosci. 21, 1072–1083 (2018).

    Article  PubMed  Google Scholar 

  6. Autry, A. E. et al. Nature 475, 91–95 (2011).

    Article  PubMed  Google Scholar 

  7. Ford, C. P. Neuroscience 282, 13–22 (2014).

    Article  PubMed  Google Scholar 

  8. Mameli, M. et al. Nature Neurosci. 12, 1036–1041 (2009).

    Article  PubMed  Google Scholar 

  9. Pascoli, V. et al. Nature 509, 459–464 (2014).

    Article  PubMed  Google Scholar 

  10. Venniro, M., Banks, M. L., Heilig, M., Epstein, D. H. & Shaham, Y. Nature Rev. Neurosci. 21, 625–643 (2020).

    Article  PubMed  Google Scholar 

  11. De Luca, M. T. & Badiani, A. Psychopharmacology 214, 549–556 (2011).

    Article  PubMed  Google Scholar 

  12. Berman, R. M. et al. Biol. Psychiatry 47, 351–354 (2000).

    Article  PubMed  Google Scholar 

  13. Graziane, N. M. et al. Nature Neurosci. 19, 915–925 (2016).

    Article  PubMed  Google Scholar 

  14. Kruyer, A., Kalivas, P. W. & Scofield, M. D. Neuropsychopharmacology https://doi.org/10.1038/s41386-022-01338-w (2022).

    Article  Google Scholar 

  15. Price, R. B. & Duman, R. Mol. Psychiatry 25, 530–543 (2020).

    Article  PubMed  Google Scholar 

  16. Kalivas, P. W. & Volkow, N. D. Am. J. Psychiatry 162, 1403–1413 (2005).

    Article  PubMed  Google Scholar 

Download references

Competing Interests

The authors declare no competing interests.

Subjects

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links