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How months-long COVID infections could seed dangerous new variants

Tracking SARS-CoV-2 evolution during persistent cases provides insight into the origins of Omicron and other global variants. What can scientists do with this knowledge?
  1. Ewen Callaway
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Virologist Sissy Sonnleitner tracks nearly every COVID-19 case in Austria’s rugged eastern Tyrol region. So, when one woman there kept testing positive for months on end, Sonnleitner was determined to work out what was going on.

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Nature 606, 452-455 (2022)

doi: https://doi.org/10.1038/d41586-022-01613-2

References

  1. Sonnleitner, S. T. et al. Nature Commun. 13, 2560 (2022).

    Article  PubMed  Google Scholar 

  2. Martin, M. A. & Koelle, K. Sci. Transl. Med. 13, eabh1803 (2021).

    Article  PubMed  Google Scholar 

  3. Wilkinson, S. A. J. et al. Preprint at medRxiv https://doi.org/10.1101/2022.03.02.22271697 (2022).

  4. Kemp, S. A. et al. Nature 592, 277–282 (2021).

    Article  PubMed  Google Scholar 

  5. Choi, B. et al. N. Engl. J. Med. 383, 2291–2293 (2020).

    Article  PubMed  Google Scholar 

  6. Tian, F. et al. eLife 10, e69091 (2021).

    Article  PubMed  Google Scholar 

  7. Hill, V. et al. Preprint at bioRxiv https://doi.org/10.1101/2022.03.08.481609 (2022).

  8. Martin, D. P. et al. Mol. Biol. Evol. 39, msac061 (2022).

    Article  PubMed  Google Scholar 

  9. Meng, B. et al. Nature 603, 706–714 (2022).

    Article  PubMed  Google Scholar 

  10. Gonzalez-Reiche, A. S. Preprint at medRxiv https://doi.org/10.1101/2022.05.25.22275533 (2022).

  11. Harari, S. et al. Preprint at medRxiv https://doi.org/10.1101/2022.02.17.22270829 (2022).

  12. Graf, T. et al. Virus Evol. 7, veab091 (2021).

    Article  PubMed  Google Scholar 

  13. Gandhi, S. et al. Nature Commun. 13, 1547 (2022).

    Article  PubMed  Google Scholar 

  14. Huygens, S. et al. Preprint at medRxiv https://doi.org/10.1101/2022.04.06.22273503 (2022).

  15. Rodionov, R. N. et al. Lancet Microbe 2, E138 (2021).

    Article  PubMed  Google Scholar 

  16. Bradley, R. E. et al. J. Clin. Immunol. 42, 32–35 (2022).

    Article  PubMed  Google Scholar 

Download references

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