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Twenty-five years of nanoscale thermodynamics

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Nature 604, 46-47 (2022)



  1. Jarzynski, C. Phys. Rev. Lett. 78, 2690–2693 (1997).

    Article  Google Scholar 

  2. Liphardt, J., Dumont, S., Smith, S. B., Tinoco, I. Jr, & Bustamante, C. Science, 296, 1832–1835 (2002).

    Article  PubMed  Google Scholar 

  3. Pietzonka, P., Barato, A. C. & Seifert, U. J. Stat. Mech. 2016, 124004 (2016).

    Article  Google Scholar 

  4. Evans, D. J., Cohen, E. G. D. & Morriss, G. P. Phys. Rev. Lett. 71, 2401–2404 (1993).

    Article  PubMed  Google Scholar 

  5. Gallavotti, G. & Cohen, E. G. D. Phys. Rev. Lett. 74, 2694–2697 (1995).

    Article  PubMed  Google Scholar 

  6. Crooks, G. E. Phys. Rev. E 60, 2721–2726 (1999).

    Article  Google Scholar 

  7. Seifert, U. Rep. Prog. Phys. 75, 126001 (2012).

    Article  PubMed  Google Scholar 

  8. Saira, O.-P. et al. Phys. Rev. Lett. 109, 180601 (2012).

    Article  PubMed  Google Scholar 

  9. Park, S. & Schulten, K. J. Chem. Phys. 120, 5946–5961 (2004).

    Article  PubMed  Google Scholar 

  10. Barato, A. C. & Seifert, U. Phys. Rev. Lett. 114, 158101 (2015).

    Article  PubMed  Google Scholar 

  11. Gingrich, T. R., Horowitz, J. M., Perunov, N. & England, J. L. Phys. Rev. Lett. 116, 120601 (2016).

    Article  PubMed  Google Scholar 

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Competing Interests

The authors declare no competing interests.


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