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Humans and bacteria rely on the same aeons-old immune defence

Negative stain electron microscopy of Runella gasdermin pores in DOPC liposomes

Some bacteria have a molecular pathway that creates destructive holes in cell membranes (honeycomb structure at centre) in response to pathogens — a mechanism already known in mammals Credit: A. G. Johnson et al./Science

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Nature 601, 300 (2022)



  1. Johnson, A. G. et al. Science (2022).

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