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Nature 597, 179-180 (2021)



  1. McEwen, B. & Lasley, E. N. The End of Stress As We Know It (Dana, 2002).

    Google Scholar 

  2. Li, W. et al. Nature 597, 239–244 (2021).

    Article  Google Scholar 

  3. Bourassa, C., McKay-McNabb, K. & Hampton, M. Can. Woman Stud. 24, 23–29 (2004).

    Google Scholar 

  4. Schneider, J., Atallah, J. & Levine, J. D. Adv. Genet. 77, 59–78 (2012).

    Article  PubMed  Google Scholar 

  5. Dawson, E. H. et al. Nature Commun. 9, 3574 (2018).

    Article  PubMed  Google Scholar 

  6. Sokolowski, M. B. Neuron 65, 780–794 (2010).

    Article  PubMed  Google Scholar 

  7. Tomova, L. et al. Nature Neurosci. 23, 1597–1605 (2020).

    Article  PubMed  Google Scholar 

  8. Hulse, B. K. et al. Preprint at bioRxiv (2020).

  9. Donlea, J. M., Thimgan, M. S., Suzuki, Y., Gottschalk, L. & Shaw, P. J. Science 332, 1571–1576 (2011).

    Article  PubMed  Google Scholar 

  10. Lee, G., Bahn, J. H. & Park, J. H. Proc. Natl Acad. Sci. USA 103, 12580–12585 (2006).

    Article  PubMed  Google Scholar 

  11. Lee, C. R., Chen, A. & Tye, K. M. Cell 184, 1500–1516 (2021).

    Article  PubMed  Google Scholar 

  12. Ramdya, P. et al. Nature 519, 233–236 (2015).

    Article  PubMed  Google Scholar 

  13. Schneider, J., Dickinson, M. H. & Levine, J. D. Proc. Natl Acad. Sci. USA 109, 17174–17179 (2012).

    Article  PubMed  Google Scholar 

  14. Danchin, E. et al. Science 362, 1025–1030 (2018).

    Article  PubMed  Google Scholar 

  15. Bellen, H. J., Tong, C. & Tsuda, H. Nature Rev. Neurosci. 11, 514–522 (2010).

    Article  PubMed  Google Scholar 

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Competing Interests

The author declares no competing interests.


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