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Flawed ivermectin preprint highlights challenges of COVID drug studies

The study’s withdrawal from a preprint platform deals a blow to the anti-parasite drug’s chances as a COVID treatment, researchers say.
  1. Sara Reardon
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Throughout the pandemic, the anti-parasite drug ivermectin has attracted much attention, particularly in Latin America, as a potential way to treat COVID-19. But scientists say that recent, shocking revelations of widespread flaws in the data of a preprint study reporting that the medication greatly reduces COVID-19 deaths dampens ivermectin’s promise — and highlights the challenges of investigating drug efficacy during a pandemic.

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Nature 596, 173-174 (2021)

doi: https://doi.org/10.1038/d41586-021-02081-w

References

  1. Elgazzar, A. et al. Preprint at Research Square https://doi.org/10.21203/rs.3.rs-100956/v3 (2020).

  2. Caly, L., Druce, J. D., Catton, M. G., Jans, D. A. & Wagstaff, K. M. Antiviral Res. 178, 104787 (2020).

    Article  PubMed  Google Scholar 

  3. Popp, M. et al. Cochrane Data. System. Rev. https://doi.org/10.1002/14651858.CD015017.pub2 (2021).

    Article  Google Scholar 

  4. Bryant, A. et al. Am. J. Ther. 28, e434–e460 (2021).

    Article  PubMed  Google Scholar 

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