Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • OUTLOOK

How stem cells could fix type 1 diabetes

Trials to replace the pancreatic β cells that are destroyed by this autoimmune disease are raising hopes of a cure.
  1. Liam Drew

    1. Liam Drew is a freelance writer near London.

    View author publications

    You can also search for this author in PubMed  Google Scholar

Insulin has been one of the most transformative discoveries in medicine. The isolation of this hormone in 1921 made type 1 diabetes (T1D) a treatable, rather than a terminal, illness. However, there is growing hope that 100 years later, insulin therapy for T1D might be on the brink of obsolescence.

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Nature 595, S64-S66 (2021)

doi: https://doi.org/10.1038/d41586-021-01842-x

This article is part of Nature Outlook: Autoimmune disease, an editorially independent supplement produced with the financial support of third parties. About this content.

References

  1. Katsarou, A. et al. Nature Rev. Dis. Primers 3, 17016 (2017).

    Article  PubMed  Google Scholar 

  2. Gamble, A., Pepper, A. R., Bruni, A. & Shapiro, A. M. J. Islets 10, 80–94 (2018).

    Article  PubMed  Google Scholar 

  3. Shapiro, A. M. J. et al. N. Engl. J. Med. 343, 230–238 (2000).

    Article  PubMed  Google Scholar 

  4. Pagliuca, F. W. et al. Cell 159, 428–439 (2014).

    Article  PubMed  Google Scholar 

  5. Rezania, A. et al. Nature Biotechnol. 32, 1121–1133 (2014).

    Article  PubMed  Google Scholar 

  6. D’Amour, K. A. et al. Nature Biotechnol. 24, 1392–1401 (2006).

    Article  PubMed  Google Scholar 

  7. Kroon, E. et al. Nature Biotechnol. 26, 443–452 (2008).

    Article  PubMed  Google Scholar 

  8. Stock, A. A. et al. Stem Cell Rep. 14, 91–104 (2020).

    Article  Google Scholar 

Download references

Subjects

Latest on:

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Advanced search

Quick links