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Mounting evidence suggests Sputnik COVID vaccine is safe and effective

Russia’s vaccine is in use in nearly 70 nations, but its adoption has been slowed by controversies and questions over rare side effects, and it has yet to garner World Health Organization approval.
  1. Bianca Nogrady
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Russia’s COVID-19 vaccine, Sputnik, has been the subject of fascination and controversy since the Russian government authorized its use last year, before early-stage trial results were even published. Evidence from Russia and many other countries now suggests it is safe and effective — but questions remain about the quality of surveillance for possible rare side effects.

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Nature 595, 339-340 (2021)

doi: https://doi.org/10.1038/d41586-021-01813-2

Updates & Corrections

  • Correction 07 July 2021: An earlier version of this story stated incorrectly that an analysis of 2.8 million doses that reported no deaths took place in Brazil. In fact, it was in Argentina. The text has been updated.

  • Correction 08 July 2021: An earlier version of this story used the figure for the number of adults randomized to the two doses of placebo in the phase III trial, instead of the figure for the number of adults who actually received two doses of placebo in that trial. That figure has been updated.

References

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  4. Montalti, M. et al. Preprint at medRxiv https://doi.org/10.1101/2021.05.03.21256509 (2021).

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