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Ranking the risk of heart disease

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Nature 594, S6-S7 (2021)


This article is part of Nature Outlook: Heart health, an editorially independent supplement produced with the financial support of third parties. About this content.


  1. Khera, A. V. et al. Nature Genet. 50, 1219–1224 (2018).

    Article  PubMed  Google Scholar 

  2. Mars, N. et al. Nature Med. 26, 549–557 (2020).

    Article  PubMed  Google Scholar 

  3. Sun, L. et al. PLoS Med. 18, e1003498 (2021).

    Article  PubMed  Google Scholar 

  4. Elliott, J. et al. J. Am. Med. Assoc. 323, 636–645 (2020).

    Article  Google Scholar 

  5. Wand, H. et al. Nature 591, 211–219 (2021).

    Article  PubMed  Google Scholar 

  6. Natarajan, P. et al. Circulation 135, 2091–2101 (2017).

    Article  PubMed  Google Scholar 

  7. Widén, E. et al. Preprint at medRxiv (2020).

  8. Dikilitas, O. et al. Am. J. Hum. Genet. 106, 707–716 (2020).

    Article  PubMed  Google Scholar 

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