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Mice with severe COVID symptoms could speed vaccine effort

A new rodent model of COVID-19 promises an easier and quicker way to test treatments and vaccines.
  1. Ewen Callaway
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Damaged tissue of SARS-CoV-2 CMA3p20 infection in mice

Lung tissue from mice infected with a newly developed strain of the coronavirus shows signs of severe damage. Credit: David Walker

Researchers have developed a strain of SARS-CoV-2 that triggers severe COVID-19 symptoms in mice — an advance that could accelerate the creation of drugs and vaccines and help to illuminate the biology of the disease.

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doi: https://doi.org/10.1038/d41586-021-01251-0

References

  1. Muruato, A. et al. Preprint at bioRxiv https://doi.org/10.1101/2021.05.03.442357 (2021).

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