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  • RESEARCH SUMMARY

Protein architecture of the yeast genome

Use of chromatin immunoprecipitation with exonuclease treatment (ChIP–exo) determines the positional organization of hundreds of chromosomal proteins throughout the Saccharomyces cerevisiae genome. The resulting ultra-high-resolution map provides insight into the regulation of genes, enhancers, replication origins, centromeres, subtelomeres and transposons.
  1. B. Franklin Pugh

    1. Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA.

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This is a summary of Rossi, M. J. et al. A high-resolution protein architecture of the budding yeast genome. Nature https://doi.org/10.1038/s41586-021-03314-8 (2021).

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doi: https://doi.org/10.1038/d41586-021-01118-4

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Competing Interests

B.F.P. has a financial interest in Peconic, LLC, which offers the ChIP–exo technology (US Patent 20100323361A1) implemented herein as a commercial service and could potentially benefit from the outcomes of this research.

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