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Base editor treats progeria in mice

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  1. Eriksson, M. et al. Nature 423, 293–298 (2003).

    PubMed  Article  Google Scholar 

  2. De Sandre-Giovannoli, A. et al. Science 300, 2055 (2003).

    PubMed  Article  Google Scholar 

  3. Gordon, L. B., Brown, W. T. & Collins, F. S. Hutchinson–Gilford Progeria Syndrome (GeneReviews, 2019).

    Google Scholar 

  4. Gordon, L. B. et al. Proc. Natl Acad. Sci. USA 109, 16666–16671 (2012).

    PubMed  Article  Google Scholar 

  5. Gaudelli, N. M. et al. Nature 551, 464–471 (2017).

    PubMed  Article  Google Scholar 

  6. Anzalone, A. V., Koblan, L. W. & Liu, D. R. Nature Biotechnol. 38, 824–844 (2020).

    PubMed  Article  Google Scholar 

  7. Grimm, D. & Zolotukhin, S. Mol. Ther. 23, 1819–1831 (2015).

    PubMed  Article  Google Scholar 

Download references

Competing Interests

D.R.L. is a co-founder of Beam Therapeutics, Prime Medicine, Pairwise Plants and Editas Medicine, companies that use genome editing.


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